Article 12.indd

Intranasal drug delivery in neuropsychiatry: focus on intranasal ketamine for refractory depression.

Intranasal drug delivery (INDD) systems offer a route to the brain that bypasses problems related to gastrointestinal absorption, first-pass metabolism, and the blood-brain barrier; onset of therapeutic action is rapid, and the inconvenience and discomfort of parenteral administration are avoided. INDD has found several applications in neuropsychiatry, such as to treat migraine, acute and chron...

Reading 12-3.indd

58-61-Fea GuiBy_11-06.indd

102 10 1 10-1 10-2 10-3 10-4 10-5 10-6 10-7 10-8 10-9 10-10 10-11 10-12 10-13 printers who were diligent in communicating with one another, the materials and processes involved in UV curing have become much better understood. This article will try to explain some of the mysteries and myths of UV curing typically confronted by printers who are new to the technology. These mysteries and myths are...

Building an integrated neurodegenerative disease database at an academic health center.

BACKGROUND It is becoming increasingly important to study common and distinct etiologies, clinical and pathological features, and mechanisms related to neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and frontotemporal lobar degeneration. These comparative studies rely on powerful database tools to quickly generate data sets that match...

Synthesis and Reactions of 3-Unsubstituted 2-Isoxazolines

Pohjakallio_176x250.indd 3 4.3.2011 10.34 Abstract_Pohjakallio_176x250.indd 3 4.3.2011 10.34Pohjakallio_176x250.indd 3 4.3.2011 10.34 2-Isoksatsoliinit ovat heterosyklisiä yhdisteitä, joita voidaan käyttää monipuolisesti synteettisinä välivaiheina erilaisten hyödyllisten rakenneyksiköiden valmistamisessa. 2-Isoksatsoliinien hyödyllisyys on pitkään perustunut niiden helppoon synteesiin erityises...

Vet Sept 2014.indd

Hypothyroidism is the most common canine endocrinopathy (population prevalence 0.2-0.8 per cent), but can be challenging to diagnose. It is important to use a combination of clinical assessment, such as signalment, presenting signs and clinical examination findings, as well as routine and then specific endocrine tests in order to make a definitive diagnosis. This article will help us to underst...